Response of GEM models of neuroblastoma to cabozantinib assessed by multiparametric magnetic resonance imaging

Response of GEM models of neuroblastoma to cabozantinib assessed by multiparametric magnetic resonance imaging

Background: In neuroblastoma MYCN amplification is associated with enhanced angiogenesis and poor survival. Mutations in the anaplastic lymphoma kinase (ALK) gene can occur with MYCN amplification, conferring a very poor prognosis. Vascular endothelial growth factor (VEGF) and hepatocyte growth fact...

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Bibliographic Details
Main Authors: Gilberto S. Almeida, Philippa King, Albert Hallsworth, Hannah Webber, Sergey Popov, Susana Miranda, Orli Yogev, Andrew D.J. Pearson, Louis Chesler, Yann Jamin, Simon P. Robinson
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Neuroblastoma
Cabozantinib
MRI
Imaging biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000491
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