De Novo MET-amplified NSCLC treated with savolitinib achieved remarkable tumor regression: a case report and review of literature

Abstract Primary MET amplification is an infrequent tumorigenic driver gene alteration identified in pulmonary neoplasms. Data on the effectiveness of MET-tyrosine kinase inhibitor (TKI) therapy in de novo MET amplification are relatively scarce, and there remains a dearth of empirical evidence supp...

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Bibliographic Details
Main Authors: Jin Sheng, Juan Jiao, Na Yan, Hongming Pan
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1007/s00432-025-06132-x
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