Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

The CSB protein, a member of the SWI/SNF ATP dependent chromatin remodeling family of proteins, plays a role in a sub-pathway of nucleotide excision repair (NER) known as transcription coupled repair (TCR). CSB is frequently mutated in Cockayne syndrome group B, a segmental progeroid human autosomal...

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Main Authors: Serena Nicolai, Silvia Filippi, Manuela Caputo, Lubos Cipak, Juraj Gregan, Gustav Ammerer, Mattia Frontini, Daniela Willems, Giorgio Prantera, Adayabalam S Balajee, Luca Proietti-De-Santis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128558
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https://doi.org/10.1371/journal.pone.0128558

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