Pre-Existing Anti-Vector Immunity to Adenovirus-Inspired VLP Vaccines Shows an Adjuvant-Dependent Antagonism

Pre-Existing Anti-Vector Immunity to Adenovirus-Inspired VLP Vaccines Shows an Adjuvant-Dependent Antagonism

<b>Background/Objectives:</b> The use of virus-like particles (VLPs) in vaccinology has expanded significantly in recent years. VLPs have the advantage of being non-infectious while effectively stimulating B cell responses through the repetitive presentation of epitope motifs on their su...

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Bibliographic Details
Main Authors: Salomé Gallet, Dalil Hannani, Sebastian Dergan-Dylon, Emilie Vassal-Stermann, Isabelle Bally, Christopher Chevillard, Daphna Fenel, Olivier Epaulard, Pascal Poignard, Pascal Fender
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
Subjects:
VLP
adenovirus
adjuvant
pre-existing immunity
SARS-CoV-2
Online Access:https://www.mdpi.com/2076-393X/13/3/238
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https://www.mdpi.com/2076-393X/13/3/238

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