Dynamic <i>In Vitro</i> PK/PD Infection Models for the Development and Optimisation of Antimicrobial Regimens: A Narrative Review

The antimicrobial concentration–time profile in humans affects antimicrobial activity, and as such, it is critical for preclinical infection models to simulate human-like dynamic concentration–time profiles for maximal translatability. This review discusses the setup, principle, and application of v...

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Bibliographic Details
Main Authors: Yalew M. Wale, Jason A. Roberts, Fekade B. Sime
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antibiotics
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Online Access:https://www.mdpi.com/2079-6382/13/12/1201
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