Regulation of pyroptosis by natural products in ulcerative colitis: mechanisms and therapeutic potential

Ulcerative colitis (UC), a chronic inflammatory bowel disease, is driven by dysregulated immune responses and persistent intestinal inflammation. Pyroptosis, a caspase/gasdermin-mediated inflammatory cell death that exacerbates mucosal damage through excessive cytokine release and epithelial barrier...

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Bibliographic Details
Main Authors: Xiaobei Lu, Yapeng Sun, Zhaoyi Zhang, Zhigang Sun, Shaohui Wang, Erping Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1573684/full
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