Myeloid cells as IFNα producers in systemic lupus erythematosus

Type I interferons (IFNs) play crucial roles in the pathogenesis of systemic lupus erythematosus (SLE). Plasmacytoid dendritic cells (pDCs) stimulated by Toll-like receptor (TLR) pathways have been thought to be the major producers of IFNα in patients with SLE. However, the responsiveness of pDCs fr...

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Bibliographic Details
Main Authors: Taiga Kuga, Asako Chiba, Goh Murayama, Sachiko Miyake
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1562221/full
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