Complex Membrane Channel Blockade: A Unifying Hypothesis for the Prodromal and Acute Neuropsychiatric Sequelae Resulting from Exposure to the Antimalarial Drug Mefloquine

The alkaloid toxin quinine and its derivative compounds have been used for many centuries as effective medications for the prevention and treatment of malaria. More recently, synthetic derivatives, such as the quinoline derivative mefloquine (bis(trifluoromethyl)-(2-piperidyl)-4-quinolinemethanol),...

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Bibliographic Details
Main Author: Jane C. Quinn
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2015/368064
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