Subacute dibutyl phthalate exposure impairs hepatic T cells and facilitates hepatitis B progression in mouse liver

Subacute dibutyl phthalate exposure impairs hepatic T cells and facilitates hepatitis B progression in mouse liver

The hepatic immune microenvironment governs liver disease susceptibility by balancing immune defense and tolerance. While phthalate esters (PAEs), emerging pollutants derived from plastics, have been acknowledged as hepatoxic substances, the immunomodulatory and clinical impacts of subacute PAEs exp...

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Bibliographic Details
Main Authors: Zhenru Zhu, Dongli Linghu, Yongyi Luo, Shibo Sun, Zheng Xie, Zhichao Sun, Chuanjiang Li, Qifan Zhang, Qiwei Yao, Dehua Wu, Chuanhui Cao, Jingyuan Sun
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
DBP
Single-cell RNA sequencing
Liver immune exhaustion
T lymphocytes
Hepatitis B
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325007341
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