Multidimensional bioinformatics analysis of chondrosarcoma subtypes and TGF-β signaling networks using big data approaches

Multidimensional bioinformatics analysis of chondrosarcoma subtypes and TGF-β signaling networks using big data approaches

Abstract Background Chondrosarcoma, a rare and heterogeneous malignant bone tumor, presents significant clinical challenges due to its complex molecular underpinnings and limited treatment options. In this study, we employ single-cell RNA sequencing (scRNA-seq) and bioinformatics analyses to delinea...

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Bibliographic Details
Main Authors: Shengke Li, Junteng Chen, Fuping He, Maosheng Wang, Jun Liu, Hui Xie
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Chondrosarcoma
Single-cell RNA sequencing
TGF-beta signaling
Cell subtypes
Bioinformatics analysis
Online Access:https://doi.org/10.1007/s12672-025-02931-3
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https://doi.org/10.1007/s12672-025-02931-3

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