Unveiling how mitotic spindle orientation in 3D human colon organoids affects matrix displacements through a 4D study using DVC

Unveiling how mitotic spindle orientation in 3D human colon organoids affects matrix displacements through a 4D study using DVC

Abstract Cell division is a major event in tissue homeostasis, enabling renewal and regeneration. In human colon, vertical division is mainly observed in the stem cell compartment while horizontal division is more frequent in the progenitor transit amplifying zone. To study cell division, the human...

Full description

Saved in:
Bibliographic Details
Main Authors: L. Magne, T. Pottier, D. Michel, J. Laussu, D. Bonnet, L. Alric, S. Segonds, G. Recher, F. Bugarin, A. Ferrand
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
4D digital volume correlation
Organoid
Extracellular matrix
Cell division
4D displacements
Online Access:https://doi.org/10.1038/s41598-025-04156-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-04156-4

Similar Items