Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient

While we are still learning about COVID-19 affecting people, older persons and persons with underlying diseases such as high blood pressure, heart disease, and diabetes mellitus (DM) appear to develop serious illness and more complications often than others. In this report, we presented a patient wi...

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Main Authors: Sirous Jafari, Zahra Jahani, Reihane Alikhani, SeyedAhmad SeyedAlinaghi, Malihe Hasannezhad, Faeze Salahshour, Ali Asadollahi-Amin
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2022/5943221
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author Sirous Jafari
Zahra Jahani
Reihane Alikhani
SeyedAhmad SeyedAlinaghi
Malihe Hasannezhad
Faeze Salahshour
Ali Asadollahi-Amin
author_facet Sirous Jafari
Zahra Jahani
Reihane Alikhani
SeyedAhmad SeyedAlinaghi
Malihe Hasannezhad
Faeze Salahshour
Ali Asadollahi-Amin
author_sort Sirous Jafari
collection DOAJ
description While we are still learning about COVID-19 affecting people, older persons and persons with underlying diseases such as high blood pressure, heart disease, and diabetes mellitus (DM) appear to develop serious illness and more complications often than others. In this report, we presented a patient with spontaneous pneumomediastinum after COVID-19. The patient was a 61-year-old man with a history of DM, hypertension, and heart failure, who has been infected with COVID-19. The patient was diagnosed with COVID-19 based on RT-PCR analysis of nasopharyngeal samples, and chest X-ray showed patchy infiltration upper and lower lobes bilaterally. By day 4, imaging was repeated, performed due to exacerbation of pleuritic chest pain, decreased O2 saturation (80%), and coughing that revealed multiple ground-glass opacities bilaterally, and interlobular septal thickening with emphysema in most of the left upper lobe and a small part of right upper lobe which led to severe spontaneous left pneumomediastinum and parenchymal consolidation was also observed. The combination of a chest tube, antibiotics (vancomycin 1 gr/bid and meropenem 1 g/bid), and antiviral (hydroxychloroquine 200 mg/bid and atazanavir 300 mg/daily) was prescribed, and continued treatment with antiviral and appropriate care for pneumomediastinum was successful. Spontaneous pneumomediastinum in the context of COVID-19 should be considered as a prognostic factor in favor of worsening diseases.
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spelling doaj-art-05da8a3ef2e74f9dada36c1f767198942025-02-03T05:53:27ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/5943221Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected PatientSirous Jafari0Zahra Jahani1Reihane Alikhani2SeyedAhmad SeyedAlinaghi3Malihe Hasannezhad4Faeze Salahshour5Ali Asadollahi-Amin6Department of Infectious DiseasesDepartment of Infectious DiseasesDepartment of Infectious DiseasesIranian Research Center for HIV/AIDSDepartment of Infectious DiseasesDepartment of RadiologyIranian Research Center for HIV/AIDSWhile we are still learning about COVID-19 affecting people, older persons and persons with underlying diseases such as high blood pressure, heart disease, and diabetes mellitus (DM) appear to develop serious illness and more complications often than others. In this report, we presented a patient with spontaneous pneumomediastinum after COVID-19. The patient was a 61-year-old man with a history of DM, hypertension, and heart failure, who has been infected with COVID-19. The patient was diagnosed with COVID-19 based on RT-PCR analysis of nasopharyngeal samples, and chest X-ray showed patchy infiltration upper and lower lobes bilaterally. By day 4, imaging was repeated, performed due to exacerbation of pleuritic chest pain, decreased O2 saturation (80%), and coughing that revealed multiple ground-glass opacities bilaterally, and interlobular septal thickening with emphysema in most of the left upper lobe and a small part of right upper lobe which led to severe spontaneous left pneumomediastinum and parenchymal consolidation was also observed. The combination of a chest tube, antibiotics (vancomycin 1 gr/bid and meropenem 1 g/bid), and antiviral (hydroxychloroquine 200 mg/bid and atazanavir 300 mg/daily) was prescribed, and continued treatment with antiviral and appropriate care for pneumomediastinum was successful. Spontaneous pneumomediastinum in the context of COVID-19 should be considered as a prognostic factor in favor of worsening diseases.http://dx.doi.org/10.1155/2022/5943221
spellingShingle Sirous Jafari
Zahra Jahani
Reihane Alikhani
SeyedAhmad SeyedAlinaghi
Malihe Hasannezhad
Faeze Salahshour
Ali Asadollahi-Amin
Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
Case Reports in Infectious Diseases
title Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
title_full Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
title_fullStr Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
title_full_unstemmed Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
title_short Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
title_sort spontaneous loculated pneumomediastinum in a covid 19 infected patient
url http://dx.doi.org/10.1155/2022/5943221
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