Next-generation diagnostics of bloodstream infections enabled by rapid whole-genome sequencing of bacterial cells purified from blood culturesResearch in context

Next-generation diagnostics of bloodstream infections enabled by rapid whole-genome sequencing of bacterial cells purified from blood culturesResearch in context

Summary: Background: Blood culture (BC) remains the cornerstone for diagnosis of bloodstream infections (BSI), but the long turn-around time (TAT) hampers timely selection of appropriate chemotherapy. Novel molecular approaches have been developed to provide faster results but are also affected by...

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Bibliographic Details
Main Authors: Vincenzo Di Pilato, Chiara Bonaiuto, Fabio Morecchiato, Alberto Antonelli, Tommaso Giani, Gian Maria Rossolini
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:EBioMedicine
Subjects:
Molecular diagnostics
Sepsis
Bacterial infections
Antimicrobial resistance
WGS
Long-read next-generation sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425000775
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http://www.sciencedirect.com/science/article/pii/S2352396425000775

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