Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells

Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells

Abstract Background The tumor microenvironment (TME) supplies critical metabolites that support cancer cell survival and progression. Adipocytes support tumor progression by secreting free fatty acids (FFAs) and adipokines; however, the role and mechanisms underlying lipid droplet (LD) release from...

Full description

Saved in:
Bibliographic Details
Main Authors: Haimeng Yin, Ying Shan, Qin Zhu, Ling Yuan, Feng Ju, Yu Shi, Yumo Han, Rui Wu, Tian Xia, Kaiwen Zhang, Yiwen You, Bo You
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cancer & Metabolism
Subjects:
Nasopharyngeal carcinoma (NPC)
Exosomes
VPS4B
ANXA5
LD release
Metabolic symbiosis
Online Access:https://doi.org/10.1186/s40170-025-00393-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s40170-025-00393-3

Similar Items