Nanoplatforms Targeting Intrinsically Disordered Protein Aggregation for Translational Neuroscience Applications

Nanoplatforms Targeting Intrinsically Disordered Protein Aggregation for Translational Neuroscience Applications

Intrinsically disordered proteins (IDPs), such as tau, beta-amyloid (Aβ), and alpha-synuclein (αSyn), are prone to misfolding, resulting in pathological aggregation and propagation that drive neurodegenerative diseases, including Alzheimer’s disease (AD), frontotemporal dementia (FTD), and Parkinson...

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Bibliographic Details
Main Authors: Chih Hung Lo, Lenny Yi Tong Cheong, Jialiu Zeng
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Nanomaterials
Subjects:
nanoplatform
intrinsically disordered protein
oligomerization
fibrillization
aggregation
nanomedicine
Online Access:https://www.mdpi.com/2079-4991/15/10/704
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https://www.mdpi.com/2079-4991/15/10/704

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