Synthesis and antimycotic activity of new derivatives of imidazo[1,2-a]pyrimidines

Synthesis and antimycotic activity of new derivatives of imidazo[1,2-a]pyrimidines

The heterocyclic core of imidazo[1,2-a]pyrimidine was formed in satisfactory yields as a result of the interaction of the readily available 2-aminoimidazole with N-substituted maleimides or N-arylitaconimides. The mechanism of the studied processes was postulated basing on experimental data, HPLC–MS...

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Main Authors: Dmitriy Yu. Vandyshev, Daria A. Mangusheva, Khidmet S. Shikhaliev, Kirill A. Scherbakov, Oleg N. Burov, Alexander D. Zagrebaev, Tatiana N. Khmelevskaya, Alexey S. Trenin, Fedor I. Zubkov
Format: Article
Language:English
Published: Beilstein-Institut 2024-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
2-aminoimidazole
antimycotic activity
imidazo[1,2-a]pyrimidine
molecular docking
n-arylitaconimides
n-substituted maleimides
recyclization
Online Access:https://doi.org/10.3762/bjoc.20.236
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https://doi.org/10.3762/bjoc.20.236

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