Immune Cell-Mediated Effect of Lipid Profile on Colorectal Cancer: A Two-Step, Two-Sample Mendelian Randomization Study

Immune Cell-Mediated Effect of Lipid Profile on Colorectal Cancer: A Two-Step, Two-Sample Mendelian Randomization Study

ObjectiveTo elucidate the bidirectional causal relationship between lipid profiles and colorectal cancer (CRC) by using the two-sample and two-step Mendelian randomization (MR) methods, and to explore the mediating role and proportion of immune cells as intermediary factors. MethodsThe pooled statis...

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Bibliographic Details
Main Authors: Wanli GONG, Yaqi HOU, Yue WANG, Yuan LI, Rongxuan QI, Qi YU, Juan ZHANG
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2024-10-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
colorectal cancer
mendelian randomization
causality
immune cells
liposome
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2024.24.0284
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http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2024.24.0284

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