SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis

SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis

Abstract Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent population. The clinical outcomes for individuals with relapsed or refractory ES are notably adverse, primarily attributed to the constrained thera...

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Main Authors: Huimou Chen, Jing Hu, Xilin Xiong, Hongling Chen, Qiaofang Liao, Biaojun Lin, Yusong Chen, Yanting Peng, Yang Li, Di Cheng, Zhihua Li
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06882-5
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https://doi.org/10.1038/s41419-024-06882-5

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