ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway

ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway

Abstract This study analyzes the expression and functional role of activating transcription factor 6 (ATF6) in diffuse large B-cell lymphoma (DLBCL) and its effects on disease progression. ATF6, a core component of the unfolded protein response (UPR) pathway, participates in many cellular activities...

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Bibliographic Details
Main Authors: Shuang Su, Lili Wu, Chen Huang, Cuiying He, Lianjing Wang, Weijing Li, Wei Liu, Lihong Liu
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Diffuse large B-cell lymphoma
ATF6
CeapinA7
Oncogene
Therapeutic target
Online Access:https://doi.org/10.1007/s12672-025-02264-1
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https://doi.org/10.1007/s12672-025-02264-1

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