Formulation and evaluation of atorvastatin calcium trihydrate Form I tablets.

Solid forms transformations and new crystal structures of an active pharmaceutical ingredient (API) can occur due to various manufacturing process conditions, especially if the drug substance is formulated as a hydrate. The conversion between hydrate and anhydrate forms caused by changes in temperat...

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Bibliographic Details
Main Authors: Karen Andrea Salazar-Barrantes, Ariadna Abdala-Saiz, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos, Andrea Mariela Araya-Sibaja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0317407
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