Tumor-Induced Osteomalacia in a Patient With FGF23-Amplified Lung Adenocarcinoma and FGF23-Deleted SCLC: Case Report

Tumor-Induced Osteomalacia in a Patient With FGF23-Amplified Lung Adenocarcinoma and FGF23-Deleted SCLC: Case Report

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by ectopic fibroblast growth factor-23 (FGF23) production. We report a unique case of a 78-year-old female patient with refractory hypophosphatemia, ultimately diagnosed as TIO, in the context of two metastatic primary...

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Main Authors: Marcello Moro Queiroz, MD, Ricardo Dahmer Tiecher, MD, João Felipe Lima Feldmann, MD, Elisangela Monteiro Coser, BSc, Mariana Vargas Cruz, PhD, Livia Loureiro, PhD, Gabriela Franco Katz, MD, Marina Henkin Behar, MD, João Victor Machado Alessi, MD, Leonardo de Abreu Testagrossa, PhD, Anamaria Aranha Camargo, PhD, Paula Fontes Asprino, PhD, Fabiana Bettoni, PhD, Artur Katz, MD
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:JTO Clinical and Research Reports
Subjects:
Tumor-induced osteomalacia
Lung adenocarcinoma
Fibroblast growth factor-23
Case report
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364325000384
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