Adipocyte Angptl8 deletion improves glucose and energy metabolism and obesity associated inflammation in mice

Summary: Angiopoietin-like protein 8 (Angptl8), expressed in the liver and adipocytes, forms a complex with Angptl3 or Angptl4, which regulates lipoprotein lipase and triglyceride metabolism. However, the precise functions of adipocyte Angptl8 remain elusive. Here we report that adipocyte-specific i...

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Main Authors: Anindya Ghosh, Isabelle Chénier, Yat Hei Leung, Abel K. Oppong, Marie-Line Peyot, S. R. Murthy Madiraju, Irina Al-Khairi, Jehad Abubaker, Fahd Al-Mulla, Marc Prentki, Mohamed Abu-Farha
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025173
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