Hybrid Capture-Based Sequencing Enables Highly Sensitive Zoonotic Virus Detection Within the One Health Framework

Hybrid Capture-Based Sequencing Enables Highly Sensitive Zoonotic Virus Detection Within the One Health Framework

Hybrid capture-based target enrichment prior to sequencing has been shown to significantly improve the sensitivity of detection for genetic regions of interest. In the context of One Health relevant pathogen detection, we present a hybrid capture-based sequencing method that employs an optimized pro...

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Bibliographic Details
Main Authors: Weiya Mao, Jin Wang, Ting Li, Jiani Wu, Jiangrong Wang, Shubo Wen, Jicheng Huang, Yongxia Shi, Kui Zheng, Yali Zhai, Xiaokang Li, Yan Long, Jiahai Lu, Cheng Guo
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pathogens
Subjects:
viral metagenomics
capture probes
one health
viral diagnostics
Online Access:https://www.mdpi.com/2076-0817/14/3/264
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