Analyses of biomarkers for tremor using local field potentials recorded from deep brain stimulation electrodes in the thalamus

Analyses of biomarkers for tremor using local field potentials recorded from deep brain stimulation electrodes in the thalamus

Background: Deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) of the thalamus (TH) is an effective therapy for suppressing tremor. One of the critical challenges to optimizing VIM-DBS therapy is the lack of robust neural biomarkers that correlate well with tremor. Objective: To...

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Bibliographic Details
Main Authors: Karthik Kumaravelu, Stephen L. Schmidt, Yi Zhao, Allison Vittert, Brandon D. Swan, Chintan S. Oza, Jennifer J. Peters, Kyle T. Mitchell, Dennis A. Turner, Warren M. Grill
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Brain Stimulation
Subjects:
Essential tremor
Deep brain stimulation
Ventral intermediate and ventralis oralis posterior nuclei of the thalamus
Local field potentials
Theta
Alpha oscillations
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X25002967
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http://www.sciencedirect.com/science/article/pii/S1935861X25002967

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