Exploring intracellular anti-mycobacterium activity of lactoferricin-loaded niosomes: proteomics insights into Immunomodulation

Exploring intracellular anti-mycobacterium activity of lactoferricin-loaded niosomes: proteomics insights into Immunomodulation

Abstract Tuberculosis (TB) treatment faces significant challenges due to prolonged therapy and drug resistance, necessitating innovative anti-TB strategies. Thus, developing an innovative platform with effective anti-TB activity would offer more advantages. In this study, the pH-sensitive niosomal f...

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Main Authors: Sirikwan Sangboonruang, Natthawat Semakul, Worrapan Poomanee, Thasang Thavanapong, Sittiruk Roytrakul, Sawanya Charoenlappanit, Siriwan Thaisakun, Jiaranai Khantipongse, Nathiprada Netirat, Apiwadee Tongsong, Usanee Wattananandkul, Sorasak Intorasoot, Ponrut Phunpae, Khajornsak Tragoolpua
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Tuberculosis
Lactoferricin
Niosome
Anti-mycobacterium activity
Proteomics
Immune responses
Online Access:https://doi.org/10.1038/s41598-025-04673-2
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https://doi.org/10.1038/s41598-025-04673-2

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