iRoot SP Promotes Osteo/Odontogenesis of Bone Marrow Mesenchymal Stem Cells via Activation of NF-κB and MAPK Signaling Pathways

iRoot SP Promotes Osteo/Odontogenesis of Bone Marrow Mesenchymal Stem Cells via Activation of NF-κB and MAPK Signaling Pathways

The regeneration of bone and tooth tissues, and related cellular therapies, has attracted widespread attention. Bone marrow mesenchymal stem cells (BMSCs) are potential candidates for such regeneration. iRoot SP is a premixed bioceramic root canal sealer widely used in clinical settings. However, th...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xiao Wu, Ming Yan, Jiamin Lu, Xingyun Ge, Yuzhi Li, Minxia Bian, Lin Fu, Jinhua Yu
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2020/6673467
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Resveratrol treats peri-implantitis in mice via inhibiting the MAPKs/NF-κB signaling pathway
by: LIU Senqing, ZHANG Hua, CHEN Yanyan, HE Haipeng, HUANG Jiamin, YUAN Jingyi, HU Tianyong, DU Ruitian
Published: (2024-11-01)

Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways
by: Liang Zhu, et al.
Published: (2025-02-01)

Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells
by: Yuanxiu Zhong, et al.
Published: (2025-02-01)

Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters
by: Chaogang Wang, et al.
Published: (2024-11-01)

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
by: Xia Huang, et al.
Published: (2017-01-01)

Ononin delays the development of osteoarthritis by down-regulating MAPK and NF-κB pathways in rat models.
by: Fang Xu, et al.
Published: (2024-01-01)

Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration
by: Gang Lei, et al.
Published: (2020-01-01)

Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway
by: Jiameng Ding, et al.
Published: (2022-01-01)

Mechanisms Underlying the Osteo- and Adipo-Differentiation of Human Mesenchymal Stem Cells
by: Yu Zhang, et al.
Published: (2012-01-01)

Therapeutic effects of chlorogenic acid on allergic rhinitis through TLR4/MAPK/NF-κB pathway modulation
by: Xiaoyan Xu, et al.
Published: (2024-12-01)

Asparagus officinalis polysaccharide-loaded liposomal gels alleviate skin inflammation via inhibiting the NF-κB/MAPK pathways
by: Rongrui Zhang, et al.
Published: (2025-02-01)

Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis
by: Liu Mengdan, et al.
Published: (2024-05-01)

Ilex asprella-derived polysaccharide activates macrophage via TLR4-mediated NF-κB and MAPK signaling pathways
by: Yao Wang, et al.
Published: (2024-11-01)

Potential risk factors in systemic hypoplasia and dental caries at odontogenesis stage
by: Kovach I.V., et al.
Published: (2013-03-01)

Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling
by: Yong-Heng Luo, et al.
Published: (2018-01-01)

Nursing cooperation of four-handed procedure for apical barrier technique under dental microscope combined with iRoot BP plus (实施显微镜下根尖屏障术联合应用iRoot BP plus的四手操作护理配合及体会)
by: GE Xin (葛鑫), et al.
Published: (2022-11-01)

Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells
by: Yan Zhou, et al.
Published: (2024-12-01)

Flavonoid derivatives treat dextran sodium sulfate-induced experimental colitis in mice by inhibiting MAPK/NF-κB pathway activation
by: Cen Xiang, et al.
Published: (2024-12-01)

Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NF‐κB and MAPK signaling pathways
by: Xiaoqing Zhu, et al.
Published: (2025-01-01)

Luteolin Alleviates the TNF-α-Induced Inflammatory Response of Human Microvascular Endothelial Cells via the Akt/MAPK/NF-κB Pathway
by: Qing-Yu Lu, et al.
Published: (2024-01-01)

Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity
by: Wenhui Mo, et al.
Published: (2018-01-01)

HMGB1 Acts in Synergy with Lipopolysaccharide in Activating Rheumatoid Synovial Fibroblasts via p38 MAPK and NF-κB Signaling Pathways
by: Zheng-Wen He, et al.
Published: (2013-01-01)

Neu5Ac Induces Human Dental Pulp Stem Cell Osteo-/Odontoblastic Differentiation by Enhancing MAPK/ERK Pathway Activation
by: Changzhou Li, et al.
Published: (2021-01-01)

Parthenolide Is Neuroprotective in Rat Experimental Stroke Model: Downregulating NF-κB, Phospho-p38MAPK, and Caspase-1 and Ameliorating BBB Permeability
by: Lipeng Dong, et al.
Published: (2013-01-01)

Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway
by: Sang-Hoon Lee, et al.
Published: (2016-01-01)

Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF-κB, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages
by: Daniel Ngabire, et al.
Published: (2018-01-01)

Phenolic compounds from Chaenomeles speciosa alleviate inflammation in lipopolysaccharide-treated RAW264.7 macrophages via the NF-κB and MAPK pathways
by: Fuxia Hu, et al.
Published: (2023-07-01)

Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways
by: Wen-Chung Huang, et al.
Published: (2020-01-01)

Selenium-enriched oolong tea (Camellia sinensis) extract exerts anti-inflammatory potential via targeting NF-κB and MAPK pathways in macrophages
by: Qi Wang, et al.
Published: (2022-05-01)

Regulation of pyroptosis by NF-κB signaling
by: Ling Yang, et al.
Published: (2025-01-01)

The role of NF-κB in diabetic cardiomyopathy
by: Huang-Jun Liu, et al.
Published: (2024-12-01)

Modulation of Dental Pulp Stem Cell Odontogenesis in a Tunable PEG-Fibrinogen Hydrogel System
by: Qiqi Lu, et al.
Published: (2015-01-01)

Comparison of iRoot BP Plus and mineral trioxide aggregate for pulpotomy in primary molars under general anesthesia: a 3-year retrospective study
by: Yiming Zhao, et al.
Published: (2024-11-01)

GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis
by: Wen-Ke Wang, et al.
Published: (2024-12-01)

Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways
by: Yue Yu, et al.
Published: (2024-01-01)

Regulation of LPS-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells via TLR4-Mediated NF-κB and MAPK Signaling Pathways by Lactoferrin
by: Kai Zhang, et al.
Published: (2025-01-01)

Fucoidan alleviated colitis aggravated by fiber deficiency through protecting the gut barrier, suppressing the MAPK/NF-κB pathway, and modulating gut microbiota and metabolites
by: Weiyun Zheng, et al.
Published: (2025-01-01)

Glycyrrhizic Acid Promotes M1 Macrophage Polarization in Murine Bone Marrow-Derived Macrophages Associated with the Activation of JNK and NF-κB
by: Yulong Mao, et al.
Published: (2015-01-01)

NF-κB Signaling in the Brain of Autistic Subjects
by: Mazhar Malik, et al.
Published: (2011-01-01)

Expression of Proinflammatory and Regulatory Cytokines via NF-κB and MAPK-Dependent and IFN Regulatory Factor-3-Independent Mechanisms in Human Primary Monocytes Infected by Mycobacterium tuberculosis
by: Elena Giacomini, et al.
Published: (2011-01-01)