Computational discovery of potential therapeutic agents against brain-eating amoeba (Naegleria fowleri).

Naegleria fowleri is a human and animal pathogen well-known for its ability to digest neurons and astrocytes of the host's brain, causing a haemorrhagic and necrotizing inflammation called Primary Amoebic Meningoencephalitis. Although infections are rare, the mortality rate is over 97%, due to...

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Bibliographic Details
Main Authors: Jacopo Zattoni, Richard F Ludueña, Maral Aminpour, Jack A Tuszynski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327621
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