The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains

The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains

Background: Marek’s disease (MD) is a pathology affecting chickens caused by Marek’s disease virus (MDV), an acute transforming alphaherpesvirus of the genus <i>Mardivirus</i>. MD is characterized by paralysis, immune suppression, and the rapid formation of T-cell (primarily CD4+) lympho...

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Main Authors: Joseph N. Patria, Luka Jwander, Ifeoma Mbachu, Levi Parcells, Brian Ladman, Jakob Trimpert, Benedikt B. Kaufer, Phaedra Tavlarides-Hontz, Mark S. Parcells
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Viruses
Subjects:
Marek’s disease
Marek’s disease virus
<i>meq</i> oncogene
virulence
virulence evolution
Online Access:https://www.mdpi.com/1999-4915/17/1/56
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https://www.mdpi.com/1999-4915/17/1/56

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