HACD2 Promotes Pancreatic Cancer Progression by Enhancing PKM2 Dissociation From PRKN in a Dehydratase‐Independent Manner

Abstract 3‐Hydroxyacyl‐CoA dehydratase 2 (HACD2), an obesity‐related gene involved in the elongation of long‐chain fatty acids, is highly expressed in pancreatic cancer (PC) and is associated with patient prognosis. Interestingly, the study reveals that HACD2 mediated the proliferation of PC cells i...

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Bibliographic Details
Main Authors: Xuanning Chu, Jinyu Zhao, Yuting Shen, Qi Feng, Changlin Zhou, Lingman Ma, Yiran Zhou
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202407942
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