Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach

Abstract Systemic inflammatory response syndrome (SIRS) and organ dysfunction make it challenging to predict which major trauma patients are at risk of developing sepsis. Additionally, the unclear pathogenesis of sepsis after trauma contributes to its high morbidity and mortality. Identifying early...

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Bibliographic Details
Main Authors: Yi Gou, Bo-Hui Lv, Jun-Fei Zhang, Sheng-Ming Li, Xiao-Ping Hei, Jing-Jing Liu, Lei Li, Jian-Zhong Yang, Ke Feng
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-92631-3
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