Cystatin from Austrelaps superbus snake venom as a model for identifying potential inhibitors of Trypanosoma cruzi cruzain

Abstract Background: Chagas disease (CD), caused by Trypanosoma cruzi, affects approximately seven million individuals worldwide, with the highest number of cases in Latin America. CD has two phases, of which the chronic phase is characterized by reduced efficacy in drug therapies. This and other f...

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Main Authors: Jorge Javier Alfonso Ruiz Díaz, Ana Fidelina Gómez Garay, Anderson Makoto Kayano, Rudson Holanda, Aleff Ferreira Francisco, Christian Collins Kuehn, Andreimar Martins Soares, Celeste Vega, Leonardo de Azevedo Calderon
Format: Article
Language:English
Published: SciELO 2025-02-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992025000100303&lng=en&tlng=en
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