<i>CD46</i> Gene Editing Confers Ex Vivo BVDV Resistance in Fibroblasts from Cloned Angus Calves

A previous study demonstrated that a 19-nucleotide edit, encoding a six amino acid substitution in the bovine <i>CD46</i> gene, dramatically reduced bovine viral diarrhea virus (BVDV) susceptibility in a cloned Gir (<i>Bos indicus</i>) heifer. The present study aimed to repli...

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Bibliographic Details
Main Authors: Aspen M. Workman, Michael P. Heaton, Brian L. Vander Ley
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Viruses
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Online Access:https://www.mdpi.com/1999-4915/17/6/775
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