Effects of TrkB-related induced metaplasticity within the BLA on anxiety, extinction learning, and plasticity in BLA-modulated brain regions

Effects of TrkB-related induced metaplasticity within the BLA on anxiety, extinction learning, and plasticity in BLA-modulated brain regions

Abstract Background Neuronal plasticity within the basolateral amygdala (BLA) is fundamental for fear learning. Metaplasticity, the regulation of plasticity states, has emerged as a key mechanism mediating the subsequent impact of emotional and stressful experiences. After mRNA knockdown of synaptic...

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Main Authors: Joyeeta Dutta Hazra, Kuldeep Shrivastava, Lisa-Sophie Wüstner, Rachel Anunu, Erez Chervinsky, Somoday Hazra, Simone Beuter, Martin Kriebel, Mouna Maroun, Hansjuergen Volkmer, Gal Richter-Levin
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Behavioral and Brain Functions
Subjects:
BLA
TrkB
Metaplasticity
Transregional metaplasticity
mPFC
Fear extinction
Online Access:https://doi.org/10.1186/s12993-025-00267-0
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https://doi.org/10.1186/s12993-025-00267-0

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