The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia

Demyelinating diseases such as multiple sclerosis (MS) are chronic inflammatory autoimmune diseases and involve demyelination and axonal degeneration. Microglia rapidly respond to changes in the environment by altering morphotype and function during the progressive disease stage. Although substantia...

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Bibliographic Details
Main Authors: Dandan Zhang, Yue Jia, Xingzong Sun, Haoran Li, Min Yin, Hongliang Li, Lili Dai, Li Han, Lei Wang, Menghan Qian, Jing Du, Keming Zhu, Hongkun Bao
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/3002304
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