Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes

Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes

Purpose We aimed to identify the pathogenic variants of homologous recombination (HR) genes and analyze the correlation between the pathogenic variants and clinical characteristics in Chinese breast cancer patients.Methods A cohort of 178 breast cancer patients participated in this study. We assesse...

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Bibliographic Details
Main Authors: Zhaoyun Jiang, Bing Xu, Bo Sun, Beibei Yang, Su Lu, Mengjian Li, Juan Zhang, Liqiang Qi, Qixi Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Future Science OA
Subjects:
Breast cancer
pathogenic variant
homologous recombination repair
multi-gene testing
Online Access:https://www.tandfonline.com/doi/10.1080/20565623.2025.2458432
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https://www.tandfonline.com/doi/10.1080/20565623.2025.2458432

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