MicroRNAs in anthracycline cardiotoxicity: biomarkers, mechanisms, and therapeutic advances

BackgroundAnthracycline-based chemotherapy is a highly effective treatment for numerous cancers, yet its clinical use is severely limited by cumulative, dose-dependent cardiotoxicity. MicroRNAs (miRNAs), as key post-transcriptional regulators of gene expression, play a pivotal role in the pathophysi...

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Bibliographic Details
Main Authors: Hongyun Mao, Jing Hu, Chenshuo Yu, Sicong Xie, Cheng Chang, Juanjuan Peng, Yang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1614878/full
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