Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.

The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour heterogeneity, the diversity of the cancer ce...

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Bibliographic Details
Main Authors: Christopher R S Banerji, Simone Severini, Carlos Caldas, Andrew E Teschendorff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004115
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