Single-cell multi-omics reveals that FABP1 + renal cell carcinoma drive tumor angiogenesis through the PLG-PLAT axis under fatty acid reprogramming

Abstract Renal cell carcinoma is characterized by a poor prognosis. Recently, renal cell carcinoma has been recognized as a metabolic disease associated with fatty acid metabolic reprogramming, although in-depth studies on this topic are still lacking. We found that fatty acid metabolism reprogrammi...

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Bibliographic Details
Main Authors: Yiqiu Wang, Yingchun Liang, Min Li, Jiayi Lu, Sian Zhou, Yaoyu Yu, Changwei Yang, Xinhuang Hou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Cancer
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Online Access:https://doi.org/10.1186/s12943-025-02377-9
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