Unravelling immunomodulatory effects of bisphenol A substitutes on human macrophages, T and B lymphocytes using in vitro models

Unravelling immunomodulatory effects of bisphenol A substitutes on human macrophages, T and B lymphocytes using in vitro models

This study investigates the immunomodulatory effects of BPA substitutes using in silico and in vitro approaches. A comprehensive in silico screening with Endocrine Disruptome of BPA and its 25 substitutes revealed that BPG, BPS-MAE, BPS-MPE, BPPH and PF201 have the highest potential to bind nuclear...

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Bibliographic Details
Main Authors: Nina Franko, Tijana Markovič, Pia Žižek, Anja Kodila, Irena Mlinarič Raščan, Marija Sollner Dolenc
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Bisphenol A
BPA substitutes
Pergafast201
Immunotoxicity
Cytokine
Endocrine disruption
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325007420
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http://www.sciencedirect.com/science/article/pii/S0147651325007420

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