Cigarette smoking decreases macrophage-dependent clearance to impact the biological effects of occupational and environmental particle exposures

The retention of occupational and environmental particles in the lung is a primary determinant of biological effects. In the distal respiratory tract, particle clearance includes phagocytosis by alveolar macrophages (AMs), migration to the terminal bronchiole, and transport of AMs and particles by t...

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Bibliographic Details
Main Authors: Andrew J. Ghio, Matthew Stewart, Rahul G. Sangani, Elizabeth N. Pavlisko, Victor L. Roggli
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1558723/full
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