Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis

Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis

Abstract Background Although, recently observation methods has been proposed as one of the treatment options for non-functioning pancreatic neuroendocrine neoplasms (NF-PanNENs), determining treatment strategies may be difficult for small and low-malignant NF-PanNENs; thus, clarifying the significan...

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Main Authors: Wataru Izumo, Hiromichi Kawaida, Ryo Saito, Yuki Nakata, Hidetake Amemiya, Suguru Maruyama, Koichi Takiguchi, Katsutoshi Shoda, Kensuke Shiraishi, Shinji Furuya, Yoshihiko Kawaguchi, Kunio Mochizuki, Tetsuo Kondo, Daisuke Ichikawa
Format: Article
Language:English
Published: BMC 2025-03-01
Series:World Journal of Surgical Oncology
Subjects:
Microvascular invasion
Lymphatic invasion
Perineural invasion
Recurrence
Non-functioning pancreatic neuroendocrine neoplasm
Online Access:https://doi.org/10.1186/s12957-025-03734-0
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https://doi.org/10.1186/s12957-025-03734-0

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