Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential

Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential

ABSTRACT The latent human immunodeficiency virus (HIV) reservoir presents the biggest obstacle to curing HIV chronic infection. Consequently, finding novel strategies to control the HIV reservoir is critical. Natural killer (NK) cells are essential for antiviral immunity. However, the influence of N...

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Bibliographic Details
Main Authors: Yue Wang, Yidi Li, Jiaqi Chen, Chenxi Guo, Xiaowen Yu, Zining Zhang, Yajing Fu, Xiaoxu Han, Qinghai Hu, Haibo Ding, Hong Shang, Yongjun Jiang
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mBio
Subjects:
HIV reservoir
NK cells
TIGIT
IFN-γ
Online Access:https://journals.asm.org/doi/10.1128/mbio.03226-24
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https://journals.asm.org/doi/10.1128/mbio.03226-24

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