Demographic, Premorbid, and Clinical Characteristics of Schizophrenia Spectrum Patients with High and Low Polygenic Liability to the Disorder

Demographic, Premorbid, and Clinical Characteristics of Schizophrenia Spectrum Patients with High and Low Polygenic Liability to the Disorder

Background/Objectives: Schizophrenia is a clinically heterogeneous complex disorder with a substantial polygenic basis. The discovery of phenotypes indexing genetic differences advances research into the schizophrenia etiology but has proven to be challenging. The study aimed to further clarify the...

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Bibliographic Details
Main Authors: Margarita Alfimova, Marina Gabaeva, Tatyana Lezheiko, Victoria Plakunova, Yulia Chaika, Vera Golimbet
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Diseases
Subjects:
schizophrenia
polygenic risk scores
risk factors
premorbid functioning
PANSS
Online Access:https://www.mdpi.com/2079-9721/13/3/66
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