Plasma concentrations of extracellular vesicles correlate with inflammatory markers in patients with aortic stenosis undergoing surgical aortic valve replacement

Plasma concentrations of extracellular vesicles correlate with inflammatory markers in patients with aortic stenosis undergoing surgical aortic valve replacement

INTRODUCTION: In severe aortic stenosis (AS), turbulent flow through the calcified valve leaflets creates shear stress and causes abnormal activation and destruction of blood elements. Activated and damaged blood cells release extracellular vesicles (EVs), which are novel biomarkers of systemic infl...

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Main Authors: Tomasz Urbanowicz, Anna Olasińska-Wiśniewska, Ewelina Błażejowska, Aleksandra Gąsecka, Michał Michalak, Krzysztof J. Filipiak, Michał Rodzki, Anna Witkowska, Michał Bociański, Andrzej Tykarski, Marek Jemielity
Format: Article
Language:English
Published: Via Medica 2025-07-01
Series:Folia Cardiologica
Subjects:
aortic stenosis
aortic valve replacement
extracellular vesicles
systemic inflammatory response
Online Access:https://journals.viamedica.pl/folia_cardiologica/article/view/102238
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https://journals.viamedica.pl/folia_cardiologica/article/view/102238

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