Thinning of the temporal and insular cortex is associated with negative symptoms and impaired attention in Chinese chronic schizophrenia patients with deficit syndrome

Thinning of the temporal and insular cortex is associated with negative symptoms and impaired attention in Chinese chronic schizophrenia patients with deficit syndrome

Abstract Background The considerable clinical heterogeneity of schizophrenia poses significant challenges for elucidating its neurobiology. The concept of deficit schizophrenia (DS) is a valuable framework for addressing the heterogeneity of schizophrenia. Growing evidence suggests notable differenc...

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Bibliographic Details
Main Authors: Jin Li, Xiaobin Zhang, Junjie Wang, Haidong Yang, Man Yang, Ju Gao, Xiangdong Du
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Psychiatry
Subjects:
Deficit schizophrenia
Nondeficient schizophrenia
Brain cortical thickness
Negative symptoms
Neuropsychological assessment
Online Access:https://doi.org/10.1186/s12888-025-06835-y
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https://doi.org/10.1186/s12888-025-06835-y

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