RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stress

RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stress

Abstract Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson’s Disease (PD). Interestingly, subjects with idiopathic PD display reduced levels of RGS10 in...

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Bibliographic Details
Main Authors: Janna E. Jernigan, Hannah A. Staley, Zachary Baty, MacKenzie L. Bolen, Beatriz Nuñes Gomes, Jenny Holt, Cassandra L. Cole, Noelle K. Neighbarger, Kruthika Dheeravath, Andrea R. Merchak, Kelly B. Menees, Stephen A. Coombes, Malú Gámez Tansey
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
Subjects:
Regulator of G protein signaling 10 (RGS10)
Chronic systemic inflammation
Immune dysregulation
Neuroinflammation
Neurodegenerative diseases
Parkinson’s disease
Online Access:https://doi.org/10.1186/s12974-024-03322-1
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https://doi.org/10.1186/s12974-024-03322-1

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