Activation of estrogen-related receptor γ by calcium and cadmium

Activation of estrogen-related receptor γ by calcium and cadmium

ObjectiveEstrogen-related receptor γ (ERRγ) is a metabolic regulator with no identified physiological ligands. This study investigates whether calcium is an ERRγ ligand that mediates the effects of glucagon and whether cadmium, which mimics the effects of calcium, disrupts metabolism through ERRγ.Me...

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Main Authors: Qiaochu Wang, Nanxi Huang, John B. Psaltis, Reem M. Gahtani, Gai Yan, Dajun Lu, Shannon R. Cahalan, Xu Shi, Robert L. Copeland, Bassem R. Haddad, Mary Beth Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Endocrinology
Subjects:
estrogen-related receptor γ
gluconeogenesis
metals
calcium
cadmium
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1400022/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1400022/full

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