Structural characterization and epitope mapping of the AAVX affinity purification ligand

The application of adeno-associated virus (AAV) vectors in human gene therapies requires reproducible and homogeneous preparations for clinical efficacy and safety. For the AAV production process, often scalable affinity chromatography columns are utilized, such as the POROS CaptureSelect AAVX affin...

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Bibliographic Details
Main Authors: Mario Mietzsch, Manasi Kamat, Kari Basso, Paul Chipman, Juha T. Huiskonen, Robert McKenna
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S2329050124001931
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