Identification of HLA-B*13:01 allele in leprosy patients with dapsone hypersensitivity syndrome in Ambon, Indonesia

Identification of HLA-B*13:01 allele in leprosy patients with dapsone hypersensitivity syndrome in Ambon, Indonesia

BackgroundIndonesia ranks third globally in leprosy, with the eastern part of the country, particularly Ambon, still reporting high prevalence rates. In Ambon, the capital city of Maluku Province, the prevalence is 8.27 per 10.000 persons, exceeding the national rate of 0.61. While multidrug therapy...

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Main Authors: Sri Linuwih Susetyo Wardhani Menaldi, Mufqi Handaru Priyanto, Sandra Widaty, Yunia Irawati, Yulia Ariani Aswin, Dwi Anita Suryandari, Melani Marissa, Iwan Ariawan, Emiliana Kartika, Malika Sabrina Yunifananda, Hok Bing Thio
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Tropical Diseases
Subjects:
HLA-B*13:01
leprosy
dapsone hypersensitivity syndrome
Ambon
Indonesia HLA-B13:01 DHS patients
Online Access:https://www.frontiersin.org/articles/10.3389/fitd.2025.1597392/full
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https://www.frontiersin.org/articles/10.3389/fitd.2025.1597392/full

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