A comprehensive analysis of transcription factors identified TCF3 as a prognostic target for glioma

Abstract Transcription factors (TFs) are pivotal in tumor initiation and progression, regulating downstream gene expression and modulating cellular processes. In this study, we conducted a comprehensive analysis of TF gene sets to define the molecular subtypes of gliomas. Using nonnegative matrix fa...

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Bibliographic Details
Main Authors: Qiao Li, Peng Feng, Shangyu Liu, Goupeng Tian, Guoqiang Yuan, Yawen Pan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-09924-w
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